Economic Development
Economic Development through Technology Commercialization: A Proven Track Record of Success
In 1997, Dr. Charles Hamner and the North Carolina Biotechnology Center (“NCBC”) selected Eno River Capital in a competition to manage the North Carolina Bioscience Investment Fund (“NCBIF”). This innovative $26 million public-private venture partnership, anchored with a $10 million appropriation from the North Carolina General Assembly, is designed to serve three key regional economic development goals, without sacrificing market rates of return for its public and private investors:
- To commercialize life science technologies developed at North Carolina’s public and private Universities by creating new, locally-based venture-backed Companies;
- To create new, high-paying jobs for North Carolinians; and
- To attract additional investment capital into North Carolina from later-stage institutional venture investors.
By any of these three measures, NCBIF has proved a tremendous success. To date, NCBIF:
- Has helped launch ten NCBIF Portfolio Companies -- based on technologies out of Duke, ECU, NC State, UNC, and Wake Forest University. Seven of the ten would either have been started out-of-state or not at all but for the hands-on operational contributions of Eno River Capital, which assisted in University technology licensing, wrote Business Plans, recruited key management, and organized and led the first institutional financings.
- The ten NCBIF Portfolio Companies have created over 500 new jobs in North Carolina, at an average salary of over $60,000/year.
- The ten NCBIF Portfolio companies have raised approximately $100 million in syndications and follow-on financing in the first five years of the Fund’s life – “leverage” of approximately 5:1 on the original NCBIF investment.
The collaboration between Eno River Capital, which manages NCBIF, and the non-profit North Carolina Biotechnology Center, which oversees North Carolina’s investment in NCBIF, is generally acknowledged as one of the most innovative and successful economic-development oriented public-private partnerships in the country.
The Eno River/NCBC/NCBIF structure is considered a model for other states attempting similar initiatives.



